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07-01-2011, 04:34 AM
A medical examiner says something went wrong with professional wrestler "Macho Man" Randy Savage's heart before he crashed his car and declared the cause of death as heart disease.
The autopsy released Thursday reveals that 58-year-old Randy Poffo, known professionally as Randy Savage, had an enlarged heart with severe blocking of his coronary arteries. With only minor injuries from the crash, the Tampa Bay area medical examiner determined the cause of death to be heart disease.
Authorities say Savage was driving in Pinellas County May 20 when he lost consciousness and crashed into a tree. He was later pronounced dead at a hospital.
Toxicology results showed small traces of alcohol and hydrocodone in Poffo's system, but officials say the amounts wouldn't have factored into the crash.
http://sports.espn.go.com/espn/news/stor...NHeadlines
The autopsy released Thursday reveals that 58-year-old Randy Poffo, known professionally as Randy Savage, had an enlarged heart with severe blocking of his coronary arteries. With only minor injuries from the crash, the Tampa Bay area medical examiner determined the cause of death to be heart disease.
Authorities say Savage was driving in Pinellas County May 20 when he lost consciousness and crashed into a tree. He was later pronounced dead at a hospital.
Toxicology results showed small traces of alcohol and hydrocodone in Poffo's system, but officials say the amounts wouldn't have factored into the crash.
http://sports.espn.go.com/espn/news/stor...NHeadlines
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07-01-2011, 08:52 AM
It's called S-T-E-R-O-I-D-S!
07-02-2011, 07:49 PM
What does steriods got to do with an enlarged heart? Steriod dont effect the size of the heart.
07-02-2011, 10:45 PM
Tailback44 Wrote:What does steriods got to do with an enlarged heart? Steriod dont effect the size of the heart.
I don't know that it has anything to do with enlarged heart, but it has EVERYTHING to do with Heart Disease!
07-02-2011, 10:46 PM
Steroids Linked to Higher Heart Disease Risk
High Doses May Raise Risk of Heart Attack, Stroke, Study Shows
By Miranda Hitti
WebMD Health News
-- Taking high doses of steroids (glucocorticoids) seems to increase the risk of heart disease including heart attack, heart failure, and stroke, according to new research.
Steroids fight inflammation and are often prescribed for conditions including asthma, inflammatory bowel disease, and inflammatory arthritis. Prednisone and hydrocortisone are two examples of steroids.
Yet well-known adverse effects of these potent anti-inflammatory medications can increase the risk of developing high blood pressure, diabetes, and obesity -- risk factors for heart disease.
What is less well known about these drugs is whether and to what extent steroids contribute to heart disease and heart disease death. They write this is not predictable since these medications have anti-inflammatory effects on blood vessels -- inflammation of blood vessels has been found to be a key mediator of atherosclerosis.
The new study conducted by researcher Thomas MacDonald, MD, FRCPE, of Scotland's Ninewells Hospital and Medical School appears in the Nov. 16 issue of the journal Annals of Internal Medicine.
MacDonald and colleagues examined medical record data from more than 68,000 people with steroid prescriptions and about 82,000 people not taking steroids.
All patients were at least 40 years old when the data was collected by Scotland's National Health Service from 1993 to 1996.
Steroid types, doses, and length of treatment varied, so the researchers calculated equivalent doses for comparison. The scientists tracked participants' "cardiovascular events" including heart attack, heart failure, and stroke.
Heart disease risk was more than 2.5 times higher in people taking high doses of steroids compared with those not taking steroids.
"Treatment with high-dose glucocorticoids seemed to be associated with an increased risk for cardiovascular disease," write the researchers.
Patients taking the equivalent of 7.5 milligrams of prednisolone per day had "substantially higher rates of all cardiovascular diseases" during one to five years of follow-up, write the researchers.
Patients taking low doses of steroids fared better. They had a similar risk for heart disease as those not taking steroids.
However, the researchers don't say steroids cause cardiovascular disease, since other factors may have been at work. They could not establish whether the disease, for which treatment with steroids was necessary, account for the higher risk of heart disease in this group of individuals.
For instance, the scientists didn't have information on the patients' disease severity, smoking, obesity, exercise, and diet, although they tried to adjust for at least some of those factors.
High Doses May Raise Risk of Heart Attack, Stroke, Study Shows
By Miranda Hitti
WebMD Health News
-- Taking high doses of steroids (glucocorticoids) seems to increase the risk of heart disease including heart attack, heart failure, and stroke, according to new research.
Steroids fight inflammation and are often prescribed for conditions including asthma, inflammatory bowel disease, and inflammatory arthritis. Prednisone and hydrocortisone are two examples of steroids.
Yet well-known adverse effects of these potent anti-inflammatory medications can increase the risk of developing high blood pressure, diabetes, and obesity -- risk factors for heart disease.
What is less well known about these drugs is whether and to what extent steroids contribute to heart disease and heart disease death. They write this is not predictable since these medications have anti-inflammatory effects on blood vessels -- inflammation of blood vessels has been found to be a key mediator of atherosclerosis.
The new study conducted by researcher Thomas MacDonald, MD, FRCPE, of Scotland's Ninewells Hospital and Medical School appears in the Nov. 16 issue of the journal Annals of Internal Medicine.
MacDonald and colleagues examined medical record data from more than 68,000 people with steroid prescriptions and about 82,000 people not taking steroids.
All patients were at least 40 years old when the data was collected by Scotland's National Health Service from 1993 to 1996.
Steroid types, doses, and length of treatment varied, so the researchers calculated equivalent doses for comparison. The scientists tracked participants' "cardiovascular events" including heart attack, heart failure, and stroke.
Heart disease risk was more than 2.5 times higher in people taking high doses of steroids compared with those not taking steroids.
"Treatment with high-dose glucocorticoids seemed to be associated with an increased risk for cardiovascular disease," write the researchers.
Patients taking the equivalent of 7.5 milligrams of prednisolone per day had "substantially higher rates of all cardiovascular diseases" during one to five years of follow-up, write the researchers.
Patients taking low doses of steroids fared better. They had a similar risk for heart disease as those not taking steroids.
However, the researchers don't say steroids cause cardiovascular disease, since other factors may have been at work. They could not establish whether the disease, for which treatment with steroids was necessary, account for the higher risk of heart disease in this group of individuals.
For instance, the scientists didn't have information on the patients' disease severity, smoking, obesity, exercise, and diet, although they tried to adjust for at least some of those factors.
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