[EKUAlum05]

One of the toughest offenses. What's the best defense to run against it?

Any defense with fast DE's and LB's who don't overpursue and miss assignments.

Additionally, Safeties have to really be aware in this system not get sucked into play fakes.

I personally would prefer a 4-3 set with your maximum speed at your outside linebackers. The 4 down lineman should help congest the middle of the field with the read option, you can then decide whether you'd rather have 2 safeties or just 1. But once again, if you don't have outside backers with the ability to get sideline to sideline you don't have a chance.

Another defense that is almost perfectly suited for the spread option is the 3-3-5 that West Virginia runs. This particular defense is vulnerable against single back sets when the QB is under center, or any type of pro set (I formation, split backs, etc) that utilize tight ends, but against the shotgun sets it maximizes your athleticism and optimizes the number of looks you can give.